Novedades en condroprotección

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18 de diciembre de 2013

A continuación le mostramos las novedades de las revistas más importantes en Condroprotección.
	Resultado a largo plazo tras el tratamiento mediante microfracturas de lesiones condrales de rodilla que implican todo el grosor del cartílago en atletas     Knee Surg Sports Traumatol Arthrosc. 2013 Sep 20. [publicación electrónica previa a la publicación impresa]     Efectos de la dieta y ejercicio intensivos sobre la carga de a articulación de la rodilla, la inflamación y los resultados clínicos entre adultos con sobrepeso y obesos que padecen artrosis de rodilla: ensayo clínico randomizado IDEA     JAMA. 2013;310(12):1263-73. doi: 10.1001/jama.2013.277669.   Arthritis & Rheumatism Volume 65, Issue 12, December 2013 Regional Distribution of Adult Rheumatologists American College of Rheumatology Committee on Rheumatology Training and Workforce Issues   A Genome-Wide Association Study Reveals ARL15, a Novel Non-HLA Susceptibility Gene for Rheumatoid Arthritis in North Indians Sapna Negi, Garima Juyal, Sabyasachi Senapati, Pushplata Prasad, Aditi Gupta, Shalini Singh, Sujit Kashyap, Ashok Kumar, Uma Kumar, Rajiva Gupta, Satbir Kaur, Suraksha Agrawal, Amita Aggarwal, Jurg Ott, Sanjay Jain, Ramesh C. Juyal and B. K. Thelma   Indocyanine Green-Enhanced Fluorescence Optical Imaging in Patients With Early and Very Early Arthritis: A Comparative Study With Magnetic Resonance Imaging Stephanie G. Werner, Hans-Eckhard Langer, Peter Schott, Malte Bahner, Carsten Schwenke, Gudrun Lind-Albrecht, Felicitas Spiecker, Bernward Kurtz, Gerd R. Burmester and Marina Backhaus   M-Ficolin Levels Reflect Disease Activity and Predict Remission in Early Rheumatoid Arthritis Christian G. Ammitzbøll, Steffen Thiel, Jens C. Jensenius, Torkell Ellingsen, Kim Hørslev-Petersen, Merete L. Hetland, Peter Junker, Niels S. Krogh, Mikkel Østergaard and Kristian Stengaard-Pedersen   Association of Genetic Variants in the IL4 and IL4R Genes With the Severity of Joint Damage in Rheumatoid Arthritis: A Study in Seven Cohorts A. Krabben, A. G. Wilson, D. P. C. de Rooy, A. Zhernakova, E. Brouwer, E. Lindqvist, T. Saxne, G. Stoeken, J. A. B. van Nies, R. Knevel, T. W. J. Huizinga, R. Toes, P. K. Gregersen and A. H. M. van der Helm-van Mil   Identification of BACH2 and RAD51B as Rheumatoid Arthritis Susceptibility Loci in a Meta-Analysis of Genome-Wide Data Kate McAllister, Annie Yarwood, John Bowes, Gisela Orozco, Sebastian Viatte, Dorothée Diogo, Lynne J. Hocking, Sophia Steer, Paul Wordsworth, A. G. Wilson, Ann W. Morgan, UK Rheumatoid Arthritis Genetics Consortium, Rheumatoid Arthritis Consortium International, Joel M. Kremer, Dimitrios Pappas, Peter Gregersen, Lars Klareskog, Robert Plenge, Anne Barton, Jeffrey Greenberg, Jane Worthington and Stephen Eyre   A Distinct Human CD4+ T Cell Subset That Secretes CXCL13 in Rheumatoid Synovium Shio Kobayashi, Koichi Murata, Hideyuki Shibuya, Mami Morita, Masahiro Ishikawa, Moritoshi Furu, Hiromu Ito, Juichi Ito, Shuichi Matsuda, Takeshi Watanabe and Hiroyuki Yoshitomi   Local Synovial Engagement of Angiogenic TIE-2 Is Associated With the Development of Persistent Erosive Rheumatoid Arthritis in Patients With Early Arthritis Marleen G. H. van de Sande, Daphne de Launay, Maria J. H. de Hair, Samuel García, Gijs P. M. van de Sande, Carla A. Wijbrandts, Danielle M. Gerlag, Kris A. Reedquist and Paul P. Tak   The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Preserves Bone Microarchitecture in Experimental Arthritis by Reducing the Interleukin-17-Dependent Osteoclastogenic Pathway Meriem Koufany, Daniel Chappard, Patrick Netter, Claire Bastien, Georges Weryha, Jean-Yves Jouzeau and David Moulin   Tumor Necrosis Factor α Inhibition in Radiographic and Nonradiographic Axial Spondyloarthritis: Results From a Large Observational Cohort Adrian Ciurea, Almut Scherer, Pascale Exer, Jürg Bernhard, Jean Dudler, Brigitte Beyeler, Rudolf Kissling, Daniel Stekhoven, Kaspar Rufibach, Giorgio Tamborrini, Bettina Weiss, Rüdiger Müller, Michael J. Nissen, Beat A. Michel, Désirée van der Heijde, Maxime Dougados, Annelies Boonen and Ulrich Weber, on behalf of the Rheumatologists of the Swiss Clinical Quality Management Program for Axial Spondyloarthritis   Deletion of the Transforming Growth Factor β Receptor Type II Gene in Articular Chondrocytes Leads to a Progressive Osteoarthritis-like Phenotype in Mice Jie Shen, Jia Li, Baoli Wang, Hongting Jin, Meina Wang, Yejia Zhang, Yunzhi Yang, Hee-Jeong Im, Regis O'Keefe and Di Chen   Annexin A6 Interacts With p65 and Stimulates NF-κB Activity and Catabolic Events in Articular Chondrocytes Kirk A. Campbell, Takeshi Minashima, Ying Zhang, Scott Hadley, You Jin Lee, Joseph Giovinazzo, Martin Quirno and Thorsten Kirsch   Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo Rose K. Davidson, Orla Jupp, Rachel de Ferrars, Colin D. Kay, Kirsty L. Culley, Rosemary Norton, Clare Driscoll, Tonia L. Vincent, Simon T. Donell, Yongping Bao and Ian M. Clark   MicroRNA-127-5p Regulates Matrix Metalloproteinase 13 Expression and Interleukin-1β-Induced Catabolic Effects in Human Chondrocytes Su Jin Park, Eun Jeong Cheon, Mi Hyun Lee and Hyun Ah Kim   Role of Interleukin-10 in Endochondral Bone Formation in Mice: Anabolic Effect via the Bone Morphogenetic Protein/Smad Pathway Youn-Kwan Jung, Gun-Woo Kim, Hye-Ri Park, Eun-Ju Lee, Je-Yong Choi, Frank Beier and Seung-Woo Han   9G4+ Autoantibodies Are an Important Source of Apoptotic Cell Reactivity Associated With High Levels of Disease Activity in Systemic Lupus Erythematosus Scott A. Jenks, Elise M. Palmer, Elides Y. Marin, Louise Hartson, Asiya Seema Chida, Christopher Richardson and Ignacio Sanz   P2X7 Blockade Attenuates Murine Lupus Nephritis by Inhibiting Activation of the NLRP3/ASC/Caspase 1 Pathway Jijun Zhao, Hongyue Wang, Chao Dai, Hongyang Wang, Hui Zhang, Yuefang Huang, Shuang Wang, Felicia Gaskin, Niansheng Yang and Shu Man Fu   Value of Isolated IgA Anti-β2-Glycoprotein I Positivity in the Diagnosis of the Antiphospholipid Syndrome Vijaya Murthy, Rohan Willis, Zurina Romay-Penabad, Patricia Ruiz-Limón, Laura A. Martínez-Martínez, Shraddha Jatwani, Praveen Jajoria, Alan Seif, Graciela S. Alarcón, Elizabeth Papalardo, Jigna Liu, Luis M. Vilá, Gerald McGwin Jr., Terry A. McNearney, Rashmi Maganti, Prashanth Sunkureddi, Trisha Parekh, Michael Tarantino, Ehtisham Akhter, Hong Fang, Emilio B. Gonzalez, Walter R. Binder, Gary L. Norman, Zakera Shums, Marius Teodorescu, John D. Reveille, Michelle Petri and Silvia S. Pierangeli   Recommendations for Screening and Detection of Connective Tissue Disease-Associated Pulmonary Arterial Hypertension Dinesh Khanna, Heather Gladue, Richard Channick, Lorinda Chung, Oliver Distler, Daniel E. Furst, Eric Hachulla, Marc Humbert, David Langleben, Stephen C. Mathai, Rajeev Saggar, Scott Visovatti, Nezam Altorok, Whitney Townsend, John FitzGerald and Vallerie V. McLaughlin   Brief Report: A Regulatory Variant in CCR6 Is Associated With Susceptibility to Antitopoisomerase-Positive Systemic Sclerosis Eugénie Koumakis, Matthieu Bouaziz, Philippe Dieudé, Barbara Ruiz, Gabriella Riemekasten, Paolo Airo, Martina Müller-Nurasyid, Daniele Cusi, Marco Matucci-Cerinic, Inga Melchers, Erika Salvi, Konstantin Strauch, Annette Peters, Giovanna Cuomo, Eric Hachulla, Elisabeth Diot, Nicolas Hunzelmann, Paola Caramaschi, Valeria Riccieri, Jörg H. W. Distler, Ingo Tarner, Jérôme Avouac, Luc Letenneur, Philippe Amouyel, Jean-Charles Lambert, Gilles Chiocchia, Catherine Boileau and Yannick Allanore   Memory Dysfunction in Primary Sjögren’s Syndrome Is Associated With Anti-NR2 Antibodies Maria B. Lauvsnes, Stian S. Maroni, Simone Appenzeller, Mona K. Beyer, Ole J. Greve, Jan T. Kvaløy, Erna Harboe, Lasse G. Gøransson, Anne B. Tjensvoll and Roald Omdal   Role of Fms-like Tyrosine Kinase 3 Ligand as a Potential Biologic Marker of Lymphoma in Primary Sjögren’s Syndrome Gabriel J. Tobón, Alain Saraux, Jacques-Eric Gottenberg, Luca Quartuccio, Martina Fabris, Raphaèle Seror, Valérie Devauchelle-Pensec, Jacques Morel, Stéphanie Rist, Xavier Mariette, Salvatore De Vita, Pierre Youinou and Jacques-Olivier Pers   Association of Bone Morphogenetic Protein 6 With Exocrine Gland Dysfunction in Patients With Sjögren’s Syndrome and in Mice Hongen Yin, Javier Cabrera-Perez, Zhenan Lai, Drew Michael, Melodie Weller, William D. Swaim, Xibao Liu, Marcelo A. Catalán, Eduardo M. Rocha, Nevien Ismail, Sandra Afione, Noreen A. Rana, Giovanni Di Pasquale, Ilias Alevizos, Indu Ambudkar, Gabor G. Illei and John A. Chiorini   Genome-Wide Association Study of Dermatomyositis Reveals Genetic Overlap With Other Autoimmune Disorders  Frederick W. Miller, Robert G. Cooper, Jiří Vencovský, Lisa G. Rider, Katalin Danko, Lucy R. Wedderburn, Ingrid E. Lundberg, Lauren M. Pachman, Ann M. Reed, Steven R. Ytterberg, Leonid Padyukov, Albert Selva-O’Callaghan, Timothy R. D. J. Radstake, David A. Isenberg, Hector Chinoy, William E. R. Ollier, Terrance P. O’Hanlon, Bo Peng, Annette Lee, Janine A. Lamb, Wei Chen, Christopher I. Amos and Peter K. Gregersen, with the Myositis Genetics Consortium   Activation of the Ubiquitin Proteasome Pathway in a Mouse Model of Inflammatory Myopathy: A Potential Therapeutic Target Sree Rayavarapu, William Coley, Jack H. Van der Meulen, Erdinc Cakir, Kathyayini Tappeta, Travis B. Kinder, Blythe C. Dillingham, Kristy J. Brown, Yetrib Hathout and Kanneboyina Nagaraju   Aberrant Muscle Antigen Exposure in Mice Is Sufficient to Cause Myositis in a Treg Cell-Deficient Milieu Nicholas A. Young, Rahul Sharma, Alexandra K. Friedman, Benjamin H. Kaffenberger, Brad Bolon and Wael N. Jarjour   Chronic Kidney Disease and the Risk of Incident Gout Among Middle-Aged Men: A Seven-Year Prospective Observational Study Eswar Krishnan   Anti-Tumor Necrosis Factor α Targets Protein Kinase B/c-Akt-Induced Resistance of Effector Cells to Suppression in Juvenile Idiopathic Arthritis Ellen J. Wehrens, Sebastiaan J. Vastert, Gerdien Mijnheer, Jenny Meerding, Mark Klein, Nico M. Wulffraat, Berent J. Prakken and Femke van Wijk   Prevalence of the Fibromyalgia Phenotype in Patients With Spine Pain Presenting to a Tertiary Care Pain Clinic and the Potential Treatment Implications Chad M. Brummett, Jenna Goesling, Alex Tsodikov, Taha S. Meraj, Ronald A. Wasserman, Daniel J. Clauw and Afton L. Hassett   Overlapping Structural and Functional Brain Changes in Patients With Long-Term Exposure to Fibromyalgia Pain Karin B. Jensen, Priti Srinivasan, Rosa Spaeth, Ying Tan, Eva Kosek, Frank Petzke, Serena Carville, Peter Fransson, Hanke Marcus, Steven C. R. Williams, Ernest Choy, Olivier Vitton, Richard Gracely, Martin Ingvar and Jian Kong   Progressing Toward, and Recovering From, Knee Replacement Surgery: A Five-Year Cohort Study Daniel L. Riddle, Robert A. Perera, Paul W. Stratford, William A. Jiranek and Levent Dumenci   The Journal of Rheumatology December 2013; 40 (12) Ultrasound and Magnetic Resonance Imaging in the Evaluation of Psoriatic Dactylitis: Status and Perspectives Catherine J. Bakewell, Ignazio Olivieri, Sibel Z. Aydin, Christian Dejaco, Kei Ikeda, Marwin Gutierrez, Lene Terslev, Ralf Thiele, Maria Antionetta D'Agostino, and Gurjit S. Kaeley   Disease Factors in Early Rheumatoid Arthritis Are Associated with Differential Risks for Cardiovascular Events and Mortality Depending on Age at Onset: A 10-year Observational Cohort Study Sofia Ajeganova, Maria L.E. Andersson, Johan Frostegård, and Ingiäld Hafström   Correlation of Radiographic Progression with the Cumulative Activity of Synovitis Estimated by Power Doppler Ultrasound in Rheumatoid Arthritis: Difference Between Patients Treated with Methotrexate and Those Treated with Biological Agents Kei Ikeda, Daiki Nakagomi, Yoshie Sanayama, Mieko Yamagata, Ayako Okubo, Taro Iwamoto, Hirotoshi Kawashima, Kentaro Takahashi, andHiroshi Nakajima   Chronic Widespread Pain in Patients with Rheumatoid Arthritis and the Relation Between Pain and Disease Activity Measures over the First 5 Years Maria L.E. Andersson, Björn Svensson, and Stefan Bergman   Screening for Latent Tuberculosis Infection in Patients with Chronic Inflammatory Arthritis: Discrepancies Between Tuberculin Skin Test and Interferon-γ Release Assay Results Félicie Costantino, Marcelo de Carvalho Bittencourt, Anne-Christine Rat,Damien Loeuille, Hervé Dintinger, Marie C. Béné, Gilbert Faure, and Isabelle Chary-Valckenaere   Clinical Investigation of Nontuberculous Mycobacterial Lung Disease in Japanese Patients with Rheumatoid Arthritis Receiving Biologic Therapy Hideaki Yamakawa, Noboru Takayanagi, Takashi Ishiguro, Tetsu Kanauchi,Toshiko Hoshi, and Yutaka Sugita   COMP-C3b Complexes in Rheumatoid Arthritis with Severe Extraarticular Manifestations Kaisa E. Happonen, Tore Saxne, Lennart Jacobsson, Gunnar Sturfelt, Johan Rönnelid, Tom Eirik Mollnes, Dick Heinegård, Carl Turesson, and Anna M. Blom   Assessment of Coronary Risk Based on Cumulative Exposure to Lipids in Systemic Lupus Erythematosus Mandana Nikpour, Dafna D. Gladman, Dominique Ibanez, Paula J. Harvey,and Murray B. Urowitz   Clinical Features and Associated Factors of Abdominal Pain in Systemic Lupus Erythematosus Shiwen Yuan, Fan Lian, Dongying Chen, Hao Li, Qian Qiu, Zhongping Zhan,Yujin Ye, Hanshi Xu, Liuqin Liang, and Xiuyan Yang   Nailfold Capillaroscopy for Prediction of Novel Future Severe Organ Involvement in Systemic Sclerosis Vanessa Smith, Valeria Riccieri, Carmen Pizzorni, Saskia Decuman, Ellen Deschepper, Carolien Bonroy, Alberto Sulli, Yves Piette, Filip De Keyser,and Maurizio Cutolo   Higher Frequency of Peripheral Blood Interleukin 21 Positive Follicular Helper T Cells in Patients with Ankylosing Spondylitis Fei Xiao, Hai-Yu Zhang, Yi-Jun Liu, Ding Zhao, Yu-Xing Shan, and Yan-Fang Jiang   Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis: Part of a Common Spectrum or Distinct Diseases? Dinny Wallis, Nigil Haroon, Renise Ayearst, Adele Carty, and Robert D. Inman   Patients with Antineutrophil Cytoplasmic Antibodies Associated Vasculitis in Remission Are Hypercoagulable Marc Hilhorst, Kristien Winckers, Benjamin Wilde, René van Oerle, Hugo ten Cate, and Jan Willem Cohen Tervaert   Treatment of Refractory Takayasu Arteritis with Tocilizumab: 7 Italian Patients from a Single Referral Center Enrico Tombetti, Stefano Franchini, Maurizio Papa, Maria Grazia Sabbadini,and Elena Baldissera   Myocardial Perfusion Imaging in Takayasu Arteritis Cloé Comarmond, Odile Dessault, Jean-Yves Devaux, Nathalie Costedoat-Chalumeau, Matthieu Resche-Rigon, Richard Isnard, Fabien Koskas, Patrice Cacoub, and David Saadoun   Rheumatic and Musculoskeletal Features of Whipple Disease: A Report of 29 Cases Marine Meunier, Xavier Puechal, Emmanuel Hoppé, Martin Soubrier,Philippe Dieudé, Jean Marie Berthelot, Paola Caramaschi, Jacques-Eric Gottenberg, Laure Gossec, Jacques Morel, Emilie Maury, Julien Wipff, André Kahan, and Yannick Allanore   The Effects of Monosodium Urate Monohydrate Crystals on Chondrocyte Viability and Function: Implications for Development of Cartilage Damage in Gout Ashika Chhana, Karen E. Callon, Bregina Pool, Dorit Naot, Gregory D. Gamble, Michael Dray, Rocco Pitto, Jarome Bentley, Fiona M. McQueen,Jillian Cornish, and Nicola Dalbeth   Responsiveness of Health State Utility Values in Knee Osteoarthritis Erin M. Davis, Larry D. Lynd, Maja Grubisic, Jacek A. Kopec, Eric C. Sayre,Jolanda Cibere, John Esdaile, and Carlo A. Marra   Familial Mediterranean Fever (FMF) with Proteinuria: Clinical Features, Histology, Predictors, and Prognosis in a Cohort of 25 Patients Olga Kukuy, Avi Livneh, Aharon Ben-David, Juri Kopolovic, Alexander Volkov, Yael Shinar, Eliezer Holtzman, Dganit Dinour, and Ilan Ben-Zvi   Risk Markers of Juvenile Idiopathic Arthritis-associated Uveitis in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry Sheila T. Angeles-Han, Christina F. Pelajo, Larry B. Vogler, Kelly Rouster-Stevens, Christine Kennedy, Lori Ponder, Courtney McCracken, Jorge Lopez-Benitez, Carolyn Drews-Botsch, Sampath Prahalad, The CARRA Registry Investigators, L. Abramson, M. Becker, T. Beukelman, J. Birmingham, P. Blier, A. Brown, E. Chalom, F. Dedeoglu, P. Ferguson, D. Goldsmith, B. Gottlieb, T. Graham, T. Griffin, G. Higgins, J.R. Hollister, J. Hsu, A. Huttenlocher, N. Ilowite, L. Imundo, C.J. Inman, R. Jerath, L. Jung, P. Kahn, D. Kingsbury, M. Klein-Gitelman, T. Lehman, C. Lindsley, D. McCurdy, N. Moorthy, E. Muscal, M. Nater, J. Olson, K. O'Neil, K. Onel, S. Prahalad, M. Punaro, A. Quintero, C. Rabinovich, A. Reed, S. Ringold, A. Robinson, D. Rothman, N. Ruth, K. Schikler, A. Sestak, N. Singer, S. Spalding, R. Syed, I. Szer, K. Torok, R. Vehe, E. von Scheven, J. Weiss, P. Weiss, A. White, A. Yalcindag, and L. Zemel   Osteoarthritis and Cartilage Volume 21, Issue 12, Pages 1813-2058 (December 2013)  Osteoimmunology in mucopolysaccharidoses type I, II, VI and VII. Immunological regulation of the osteoarticular system in the course of metabolic inflammation V. Opoka-Winiarska, A. Jurecka, A. Emeryk, A. Tylki-Szymańska   The clinical status of cartilage tissue regeneration in humans B. Mollon, R. Kandel, J. Chahal, J. Theodoropoulos   Anxiety and depressive symptoms before and after total hip and knee arthroplasty: a prospective multicentre study T. Duivenvoorden, M.M. Vissers, J.A.N. Verhaar, J.J.V. Busschbach, T. Gosens, R.M. Bloem, S.M.A. Bierma-Zeinstra, M. Reijman   Exclusion of patients with sequential primary total joint arthroplasties from arthroplasty outcome studies biases outcome estimates: a retrospective cohort study B. Ravi, R. Croxford, G. Hawker   The association of parity with osteoarthritis and knee replacement in the Multicenter Osteoarthritis Study B.L. Wise, J. Niu, Y. Zhang, D.T. Felson, L.A. Bradley, N. Segal, J. Keysor, M. Nevitt, N.E. Lane   Cross-cultural adaptation, reliability, internal consistency and validation of the Arabic version of the Knee injury and Osteoarthritis Outcome Score (KOOS) for Egyptian people with knee injuries A. Almangoush, L. Herrington, I. Attia, R. Jones, A. Aldawoudy, A. Abdul Aziz, A. Waley   Is increased joint loading detrimental to obese patients with knee osteoarthritis? A secondary data analysis from a randomized trial M. Henriksen, D.J. Hunter, E.B. Dam, S.P. Messier, T.P. Andriacchi, L.S. Lohmander, J. Aaboe, M. Boesen, H. Gudbergsen, H. Bliddal, R. Christensen   Differences between X-ray and MRI-determined knee cartilage thickness in weight-bearing and non-weight-bearing conditions M. Marsh, R.B. Souza, B.T. Wyman, M.-P. Hellio Le Graverand, K. Subburaj, T.M. Link, S. Majumdar   In vivo patellofemoral contact mechanics during active extension using a novel dynamic MRI-based methodology B.S. Borotikar, F.T. Sheehan   Micromechanical mapping of early osteoarthritic changes in the pericellular matrix of human articular cartilage R.E. Wilusz, S. Zauscher, F. Guilak   Cell and matrix morphology in articular cartilage from adult human knee and ankle joints suggests depth-associated adaptations to biomechanical and anatomical roles T.M. Quinn, H.-J. Häuselmann, N. Shintani, E.B. Hunziker   Consequences of chondrocyte hypertrophy on osteoarthritic cartilage: potential effect on angiogenesis L. Pesesse, C. Sanchez, J.-P. Delcour, A. Bellahcène, C. Baudouin, P. Msika, Y. Henrotin   Probing the microenvironmental conditions for induction of superficial zone protein expression R. Mhanna, E. Öztürk, P. Schlink, M. Zenobi-Wong   Moderate dynamic compression inhibits pro-catabolic response of cartilage to mechanical injury, tumor necrosis factor-α and interleukin-6, but accentuates degradation above a strain threshold Y. Li, E.H. Frank, Y. Wang, S. Chubinskaya, H.-H. Huang, A.J. Grodzinsky   Changes of early post-traumatic osteoarthritis in an ovine model of simulated ACL reconstruction are associated with transient acute post-injury synovial inflammation and tissue catabolism B.J. Heard, N.M. Solbak, Y. Achari, M. Chung, D.A. Hart, N.G. Shrive, C.B. Frank   Loss of extracellular matrix from articular cartilage is mediated by the synovium and ligament after anterior cruciate ligament injury C.M. Haslauer, K.A. Elsaid, B.C. Fleming, B.L. Proffen, V.M. Johnson, M.M. Murray   Inhibition of complement component C5 protects porcine chondrocytes from xenogeneic rejection R. Sommaggio, M. Pérez-Cruz, J.L. Brokaw, R. Máñez, C. Costa   Time-lapse observation of the dedifferentiation process in mouse chondrocytes using chondrocyte-specific reporters Y. Minegishi, K. Hosokawa, N. Tsumaki   Intra-articular injection of the selective cyclooxygenase-2 inhibitor meloxicam (Mobic) reduces experimental osteoarthritis and nociception in rats Z.-H. Wen, C.-C. Tang, Y.-C. Chang, S.-Y. Huang, C.-H. Chen, S.-C. Wu, S.-P. Hsieh, C.-S. Hsieh, K.-Y. Wang, S.-Y. Lin, H.-L. Lee, C.-H. Lee, H.-C. Kuo, W.-F. Chen, Y.-H. Jean   Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes J.H. Wang, K.S. Shih, Y.W. Wu, A.W. Wang, C.R. Yang   Scaffold-assisted cartilage tissue engineering using infant chondrocytes from human hip cartilage P.C. Kreuz, C. Gentili, B. Samans, D. Martinelli, J.P. Krüger, W. Mittelmeier, M. Endres, R. Cancedda, C. Kaps   Total knee replacement; minimal clinically important differences and responders A. Escobar, L. García Pérez, C. Herrera-Espiñeira, F. Aizpuru, C. Sarasqueta, M. Gonzalez Sáenz de Tejada, J.M. Quintana, A. Bilbao   Establishment of a reliable and reproducible murine osteoarthritis model B.J. Kim, D.-W. Kim, S.H. Kim, J.H. Cho, H.J. Lee, D.Y. Park, S.R. Park, B.H. Choi, B.-H. Min   Polyethylene wear particles play a role in development of osteoarthritis via detrimental effects on cartilage, meniscus, and synovium D.Y. Park, B.-H. Min, D.-W. Kim, B.R. Song, M. Kim, Y.J. Kim   Autophagy is activated in compression-induced cell degeneration and is mediated by reactive oxygen species in nucleus pulposus cells exposed to compression K.-G. Ma, Z.-W. Shao, S.-H. Yang, J. Wang, B.-C. Wang, L.-M. Xiong, Q. Wu, S.-F. Chen   A validated new histological classification for intervertebral disc degeneration  J.P.H.J. Rutges, R.A. Duit, J.A. Kummer, J.E.J. Bekkers, F.C. Oner, R.M. Castelein, W.J.A. Dhert, L.B. Creemers   A histological comparison of the repair tissue formed when using either Chondrogide® or periosteum during autologous chondrocyte implantation H.S. McCarthy, S. Roberts   Journal of the American Academy of Orthopaedic Surgeons December 2013; 21 (12) Pediatric Thoracolumbar Spine Trauma Alan H. Daniels, Andrew D. Sobel, and Craig P. Eberson   Iatrogenic Nerve Injuries in Shoulder Surgery William F. Scully, David J. Wilson, Stephen A. Parada,and Edward D. Arrington   Early Weight Bearing After Lower Extremity Fractures in Adults Erik N. Kubiak, Michael J. Beebe, Kylee North, Robert Hitchcock,and Michael Q. Potter   Platelet-rich Plasma in Orthopaedic Applications: Evidence-based Recommendations for Treatment Wellington K. Hsu, Allan Mishra, Scott R. Rodeo, Freddie Fu,Michael A. Terry, Pietro Randelli, S. Terry Canale, and Frank B. Kelly   Adhesive Capsulitis of the Hip: A Review Colin G. Looney, Brett Raynor, and Rebecca Lowe   Fingertip Injuries: An Update on Management Donald H. Lee, Megan E. Mignemi, and Samuel N. Crosby   Optimizing the Management of Full-Thickness Rotator Cuff Tears Jayson Murray and Leeaht Gross   Rheumatology Volume 52 Issue 12 December 2013 Effect of gender on clinical presentation in systemic lupus erythematosus Grainne Murphy and David Isenberg   Histopathological changes in tendinopathy-potential roles of BMPs? Pauline Po Yee Lui   Impact of biologic therapy on functional status in patients with rheumatoid arthritis-a meta-analysis Johanna Callhoff, Anja Weiß, Angela Zink, and Joachim Listing   The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis Faith Matcham, Lauren Rayner, Sophia Steer, and Matthew Hotopf   Urinary free light chain is a potential biomarker for ISN/RPS class III/IV lupus nephritis Masanori Hanaoka, Takahisa Gono, Yasushi Kawaguchi, Keiko Uchida, Yumi Koseki,Yasuhiro Katsumata, Hirotaka Kaneko, Kae Takagi, Hisae Ichida, Kosaku Nitta, andHisashi Yamanaka   Articular adipose tissue resident macrophages in rheumatoid arthritis patients: potential contribution to local abnormalities Ewa Kontny and Monika Prochorec-Sobieszek   Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals Bruno Filipe Bettencourt, Fabiana Leal Rocha, Helena Alves, Rosa Amorim, Joana Caetano-Lopes, Elsa Vieira-Sousa, Fernando Pimentel-Santos, Manuela Lima, Graça Porto, Jaime C. Branco, João Eurico Fonseca, and Jácome Bruges-Armas   IL-22/IL-22R1 axis and S100A8/A9 alarmins in human osteoarthritic and rheumatoid arthritis synovial fibroblasts Mar Carrión, Yasmina Juarranz, Carmen Martínez, Isidoro González-Álvaro, José L. Pablos, Irene Gutiérrez-Cañas, and Rosa P. Gomariz   Supervised physical exercise improves endothelial function in patients with systemic lupus erythematosus Edgard Torres dos Reis-Neto, Aline Evelyn da Silva, Carlos Manoel de Castro Monteiro, Luciano Monteiro de Camargo, and Emilia Inoue Sato   Development of a colour Doppler ultrasound scoring system in patients of Takayasu's arteritis and its correlation with clinical activity score (ITAS 2010) Debanjali Sinha, Sumantro Mondal, Arijit Nag, and Alakendu Ghosh   Paediatric rheumatology practice in the UK benchmarked against the British Society for Paediatric and Adolescent Rheumatology/Arthritis and Musculoskeletal Alliance Standards of Care for juvenile idiopathic arthritis Akhila Kavirayani, Helen E. 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